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Crispr-cas9 was derived from the adaptive immune systems of bacteria. The acronym crispr refers to clustered regularly interspaced short palindromic repeats. Crispr-cas9 is a unique technology that enables geneticists and medical researchers to edit parts of the genome? by removing, adding or altering. Crispr-cas9: timeline of key events ; dec 1987. The crispr mechanism first published ; 18 jan 2000. More clustered repeats of dna identified in other bacteria and. Single rna molecules comprised of both crrna and tracrrna sequences. Suitable for challenging experimental conditions (e. Crispr-cas9 was adapted from a naturally occurring genome editing system that bacteria use as an immune defense. When infected with viruses. Crispr-cas9 can be used to delete (ko) or insert (ki) genes, but with slight modifications, it can also be used to regulate the expression of genes. Crispr/cas9 is a system found in bacteria and involved in immune defence. 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